Erectile Dysfunction.4

Oral pharmacotherapy is very effective and safe method for Erectile Dysfunction, especially the advent of phosphodiesterase type 5 inhibitors: sildenafil, tadanafil and vardenafil. Sildenafil was the first PDE5 inhibitor and >20 million men have been treated in the 6yr since its launch. It is effective after 30-60 mi from administration. Tadanafil is effective from 30min after administeration, but its peak efficacy is expected in about 2 h. efficacy is maintained for up to 36h. Its efficacy is not influenced by food. Vardenafil is effective after 30min from administeration. Its effect is reduced by a heavy fatty meal.